Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 11/20 | 0.49 |
| ▸ | TERT | O14746 | 1/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.34 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10651502 | 0.84 | CYP19A1 (0.49) | CYP19A1TERTCYP17A1 | |
| SCHEMBL9529868 | 0.80 | CYP19A1 (0.48) | CYP19A1MAOB | |
| SCHEMBL11236680 | 0.80 | CYP19A1 (0.44) | CYP19A1DRD2DRD3LTB4RLTB4R2 | |
| SCHEMBL9449840 | 0.76 | CYP19A1 (0.41) | CYP19A1MAOB | |
| SCHEMBL9449843 | 0.76 | CYP19A1 (0.41) | CYP19A1MAOB | |
| SCHEMBL9449836 | 0.76 | CYP19A1 (0.41) | CYP19A1MAOB | |
| SCHEMBL11559534 | 0.75 | CYP19A1 (0.56) | CYP19A1TERTMAOAMAOB | |
| SCHEMBL11233256 | 0.71 | CYP17A1 (0.40) | CYP19A1CYP17A1 | |
| SCHEMBL11230658 | 0.70 | CYP19A1 (0.40) | CYP19A1CYP17A1 | |
| SCHEMBL2818062 | 0.70 | CYP19A1 (0.40) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105585563-B | 1- (benzofuran -5- bases) -3- phenyl -2- (1,2,4- triazol-1-yls) propenyls and its application | 湖南大学 | 2018-09-21 | — | — | CN | disclosed |
| CN-105585562-B | 1- (benzofuran -5- bases) -3- aryl -2- (triazol-1-yl) propenone and its application as anticarcinogen | 湖南大学 | 2018-09-21 | — | — | CN | disclosed |
| CN-105585562-A | 1-(benzofuran-5-yl)-3-aryl-2-(triazol-1-yl)-propenone and application thereof as anticancer drug | UNIV HUNAN | 2016-05-18 | — | — | CN | disclosed |
| CN-105585563-A | 1-(benzofuran-5-yl)-3-phenyl-2-(1,2,4-triazol-1-yl)propenol and application thereof | UNIV HUNAN | 2016-05-18 | — | — | CN | disclosed |