Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 12/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9449836 | 1.00 | CYP19A1 (0.41) | CYP19A1MAOBCYP1A2CYP2C9TSHR | |
| SCHEMBL9449843 | 1.00 | CYP19A1 (0.41) | CYP19A1MAOBCYP1A2CYP2C9TSHR | |
| SCHEMBL9529868 | 0.80 | CYP19A1 (0.48) | CYP19A1MAOB | |
| SCHEMBL28065635 | 0.76 | CYP19A1 (0.49) | CYP19A1MAOB | |
| SCHEMBL9790065 | 0.75 | CYP17A1 (0.43) | CYP19A1ALDH1A1KDM4ERECQL | |
| SCHEMBL9449549 | 0.75 | CYP17A1 (0.43) | CYP19A1ALDH1A1KDM4ERECQL | |
| SCHEMBL9450017 | 0.73 | CYP19A1 (0.40) | CYP19A1CYP1A2CYP2C9TSHRCYP2C19 | |
| SCHEMBL9450023 | 0.73 | CYP19A1 (0.40) | CYP19A1CYP1A2CYP2C9TSHRCYP2C19 | |
| SCHEMBL9450029 | 0.73 | CYP19A1 (0.40) | CYP19A1CYP1A2CYP2C9TSHRCYP2C19 | |
| SCHEMBL9449514 | 0.72 | CYP19A1 (0.40) | CYP19A1MAOBCYP1A2CYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5246956-A | N-IMIDAZOLYL DERIVATIVES OF SUBSTITUTED ALKOXYIMINO TETRAHYDRONAPHTHALENES AND CHROMANS HAVING ANTITHROMBOXANE A2 ACTIVITY | FARMITALIA CARLO ERBA S.R.L. (IT) | 1993-09-21 | — | — | US | disclosed |
| EP-0499444-A1 | N-imidazolyl derivatives of substituted alkoxyimino tetrahydronaphthalenes and chromans | PHARMACIA S.p.A. (IT) | 1992-08-19 | — | — | EP | disclosed |