Pyridine

Pyridine

SCHEMBL28065643

CCc1c[nH]c(CC)c1.c1ccncc1

nearest known ligand 0.43

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Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.37
ALDH1A1 P00352 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
TSHR P16473 1/20 0.33
NAPRT Q6XQN6 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CYP19A1 P11511 1/20 0.33
ITK Q08881 1/20 0.32
RAB9A P51151 1/20 0.31
SLC5A2 P31639 1/20 0.30
MAPT P10636 1/20 0.30
GCGR P47871 1/20 0.30
MAPK14 Q16539 1/20 0.30
HCAR2 Q8TDS4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL891414 0.84
Pyridine SCHEMBL28148424 0.82 GPR84 (0.42) TDP1HCAR2
Pyridine SCHEMBL28329515 0.82 GPR84 (0.42) TDP1HCAR2
Pyridine SCHEMBL28861162 0.80 TSHR (0.32) TSHRNAPRTTDP1
Pyridine SCHEMBL28065594 0.79 HCAR2 (0.33) TSHRNAPRTTDP1ITKHCAR2
Pyridine SCHEMBL11385854 0.73 TP53 (0.55) TP53ALDH1A1NPSR1TSHRNAPRT
Ethylbenzene SCHEMBL8652916 0.73 TP53 (0.70) TP53ALDH1A1NPSR1TSHRNAPRT
Ethylbenzene SCHEMBL28669065 0.71 TP53 (0.67) TP53ALDH1A1NPSR1TSHRNAPRT
Pyridine SCHEMBL28078338 0.71 TSHR (0.38) TP53ALDH1A1NPSR1TSHRNAPRT
Pyridine SCHEMBL28079181 0.68 TP53 (0.38) TP53ALDH1A1NPSR1TSHRNAPRT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104271608-B The method preparing conjugated diolefin polymer, the compositions comprising described conjugated diolefin polymer and the tire comprising described compositions LG化学株式会社 2016-08-31 CN disclosed