⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5610848 | 1.00 | — | — | |
| SCHEMBL15352761 | 0.71 | — | — | |
| SCHEMBL383435 | 0.71 | — | — | |
| SCHEMBL17056205 | 0.71 | — | — | |
| SCHEMBL244754 | 0.69 | — | — | |
| SCHEMBL692840 | 0.69 | — | — | |
| SCHEMBL1968046 | 0.69 | — | — | |
| SCHEMBL2398235 | 0.69 | — | — | |
| SCHEMBL4846104 | 0.69 | — | — | |
| SCHEMBL6691171 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105669521-B | Antitumoral compounds and its preparation method and application | 成都知普莱生物医药科技有限公司 | 2019-01-15 | — | — | CN | disclosed |
| CN-103965175-B | 4 (substitution phenylamino) quinazoline compounds, its preparation method and applications | 齐鲁制药有限公司 | 2017-12-22 | — | — | CN | disclosed |
| CN-105669521-A | Antitumor compound and preparation method and application thereof | 成都知普莱生物医药科技有限公司 | 2016-06-15 | — | — | CN | disclosed |
| CN-103965175-A | 4-(substituted phenylamino)quinazoline compounds, and preparation method and application thereof | QILU PHARMACEUTICAL CO LTD | 2014-08-06 | — | — | CN | disclosed |