Tetrafluoroethylene

Tetrafluoroethylene

SCHEMBL28066068

CC(C)=O.FC(F)=C(F)F

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.60
TSHR P16473 2/20 0.42
THPO P40225 1/20 0.42
FFAR3 O14843 1/20 0.42
LCK P06239 1/20 0.42
FYN P06241 1/20 0.42
CA1 P00915 2/20 0.39
ALOX15 P16050 1/20 0.39
BLM P54132 1/20 0.39
PMP22 Q01453 1/20 0.39
ALDH1A1 P00352 5/20 0.33
CA4 P22748 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
KDM4E B2RXH2 1/20 0.33
CA2 P00918 1/20 0.33
PTGS1 P23219 1/20 0.33
MMP12 P39900 1/20 0.33
NFKB1 P19838 1/20 0.31
TRPA1 O75762 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetrafluoroethylene SCHEMBL27971722 0.91 LMNA (0.50) LMNATSHRTHPOFFAR3LCK
Acetone SCHEMBL28186268 0.89
Tetrafluoroethylene SCHEMBL28004090 0.86 FFAR3 (0.64) LMNATSHRTHPOFFAR3LCK
Tetrafluoroethylene SCHEMBL27662225 0.86 LMNA (0.42) LMNATSHRTHPOFFAR3LCK
Acetone SCHEMBL27396670 0.84
Acetone SCHEMBL28087023 0.80
Acetone SCHEMBL28156343 0.80 LMNA (0.60) LMNATSHRTHPOFFAR3LCK
Acetone SCHEMBL27802017 0.80
Acetone SCHEMBL28122724 0.80
SCHEMBL13716363 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105670456-A Material capable of shielding electromagnetic waves caused by groundwater 赵文立 2016-06-15 CN disclosed