Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GPR3 | P46089 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | TYMS | P04818 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4454194 | 0.80 | KDM4E (0.52) | KDM4EGPR3MAPTHTR1ADRD2 | |
| SCHEMBL29521539 | 0.74 | CYP1A2 (0.52) | KDM4EGPR3HTR1ADRD2CYP1A2 | |
| SCHEMBL29580557 | 0.74 | CYP1A2 (0.52) | KDM4EGPR3HTR1ADRD2CYP1A2 | |
| SCHEMBL5466768 | 0.74 | CYP1A2 (0.52) | KDM4EGPR3HTR1ADRD2CYP1A2 | |
| SCHEMBL27822228 | 0.73 | KDM4E (0.57) | KDM4EGPR3NPC1LMNAMAPT | |
| SCHEMBL29845939 | 0.72 | KDM4E (0.41) | KDM4EGPR3NPC1LMNAMAPT | |
| SCHEMBL28066054 | 0.72 | KDM4E (0.41) | KDM4EGPR3NPC1LMNAMAPT | |
| Thiophene SCHEMBL27918643 | 0.69 | KDM4E (0.42) | KDM4EGPR3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL19534727 | 0.68 | CYP1A2 (0.44) | KDM4EGPR3HTR1ADRD2CYP1A2 | |
| SCHEMBL27916895 | 0.67 | KDM4E (0.38) | KDM4EGPR3MAPTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103319695-B | Conjugated polymer containing 4,9-diaza pyrene and preparation method thereof and application | 华南理工大学 | 2016-06-22 | — | — | CN | disclosed |