SCHEMBL4454194

SCHEMBL4454194

c1cc2cnc3cccc4cnc(c1)c2c43

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.52
GPR3 P46089 1/20 0.52
CYP1A2 P05177 4/20 0.43
EGFR P00533 1/20 0.41
ALDH1A1 P00352 4/20 0.40
PDE10A Q9Y233 1/20 0.39
BIRC5 O15392 1/20 0.38
MAPT P10636 2/20 0.38
HPGD P15428 2/20 0.38
CYP1A1 P04798 1/20 0.38
CYP3A4 P08684 1/20 0.38
TSHR P16473 1/20 0.38
CYP1B1 Q16678 1/20 0.38
HSD17B10 Q99714 1/20 0.38
PDGFRB P09619 2/20 0.38
PDGFRA P16234 2/20 0.38
GLA P06280 1/20 0.38
ACHE P22303 1/20 0.38
MGAM O43451 1/20 0.38
HTR1A P08908 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5466768 0.93 CYP1A2 (0.52) KDM4EGPR3CYP1A2EGFRALDH1A1
SCHEMBL29521539 0.93 CYP1A2 (0.52) KDM4EGPR3CYP1A2EGFRALDH1A1
SCHEMBL29580557 0.93 CYP1A2 (0.52) KDM4EGPR3CYP1A2EGFRALDH1A1
Thiophene SCHEMBL27918643 0.87 KDM4E (0.42) KDM4EGPR3CYP1A2EGFRALDH1A1
SCHEMBL28066054 0.85 KDM4E (0.41) KDM4EGPR3CYP1A2ALDH1A1MAPT
SCHEMBL19534727 0.85 CYP1A2 (0.44) KDM4EGPR3CYP1A2EGFRALDH1A1
SCHEMBL29845939 0.85 KDM4E (0.41) KDM4EGPR3CYP1A2ALDH1A1MAPT
SCHEMBL28066124 0.80 KDM4E (0.41) KDM4EGPR3CYP1A2MAPTHTR1A
SCHEMBL21297990 0.79 CYP1A2 (0.38) KDM4EGPR3CYP1A2ALDH1A1PDE10A
SCHEMBL21297979 0.79 CYP1A2 (0.38) KDM4EGPR3CYP1A2ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103319695-B Conjugated polymer containing 4,9-diaza pyrene and preparation method thereof and application 华南理工大学 2016-06-22 CN claimed
CN-103319695-A Conjugated polymer containing 4,9-diaza-pyrene and preparation method and application thereof UNIV SOUTH CHINA TECH 2013-09-25 CN claimed
CN-103319695-B Conjugated polymer containing 4,9-diaza pyrene and preparation method thereof and application 华南理工大学 2016-06-22 CN disclosed
CN-103319695-B Conjugated polymer containing 4,9-diaza pyrene and preparation method thereof and application 华南理工大学 2016-06-22 CN disclosed
CN-103319695-B Conjugated polymer containing 4,9-diaza pyrene and preparation method thereof and application 华南理工大学 2016-06-22 CN disclosed
CN-103319695-A Conjugated polymer containing 4,9-diaza-pyrene and preparation method and application thereof UNIV SOUTH CHINA TECH 2013-09-25 CN disclosed
CN-103319695-A Conjugated polymer containing 4,9-diaza-pyrene and preparation method and application thereof UNIV SOUTH CHINA TECH 2013-09-25 CN disclosed
CN-103319695-A Conjugated polymer containing 4,9-diaza-pyrene and preparation method and application thereof UNIV SOUTH CHINA TECH 2013-09-25 CN disclosed
US-20090221095-A1 Colorimetric Screening of DNA Binding/Intercalating Agents with Gold Nanoparticle Probes NORTHWESTERN UNIVERSITY (US) 2009-09-03 US disclosed
WO-2007047455-A9 COLORIMETRIC SCREENING OF DNA BINDING/INTERCALATING AGENTS WITH GOLD NANOPARTICLE PROBES UNIV NORTHWESTERN (US) 2007-06-14 WO disclosed
WO-2007047455-A2 COLORIMETRIC SCREENING OF DNA BINDING/INTERCALATING AGENTS WITH GOLD NANOPARTICLE PROBES NORTHWESTERN UNIVERSITY (US) 2007-04-26 WO disclosed
CN-1570140-A Double probe gene chip signal amplification method SONG KE (CN) 2005-01-26 CN disclosed
CN-1553188-A Microarray signal amplifying method 宋 克 2004-12-08 CN disclosed