SCHEMBL28066205

SCHEMBL28066205

O=CNc1ccc(Cl)nc1NC=O

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM5A P29375 2/20 0.33
PABPC1 P11940 1/20 0.33
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11993093 0.82 KDM5A (0.34) KDM5APABPC1ALDH1A1TSHR
SCHEMBL28226026 0.82 CRHBP (0.35) ALDH1A1MAPT
SCHEMBL19905777 0.78 MAPT (0.31) ALDH1A1MAPT
SCHEMBL825666 0.78 SIRT2 (0.35) ALDH1A1MAPT
SCHEMBL908706 0.74 MERTK (0.37) ALDH1A1MAPT
SCHEMBL28835842 0.73 MAPT (0.56) MAPTTSHR
SCHEMBL11993104 0.71 MAPT (0.37) MAPT
SCHEMBL22149661 0.71 PDE4D (0.36) ALDH1A1MAPTTSHR
SCHEMBL11993108 0.69 MAPK1 (0.35) ALDH1A1MAPT
SCHEMBL11993092 0.68 HDAC3 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105602552-B Fluorescent organic light-emitting material and organic electroluminescent device 友达光电股份有限公司 2018-09-07 CN disclosed
CN-105602552-A Fluorescent organic light-emitting material and organic electroluminescent device AU OPTRONICS CORP 2016-05-25 CN disclosed