Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HPGDS | O60760 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PLK1 | P53350 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | STAT6 | P42226 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28066294 | 0.85 | TSHR (0.49) | CDC25BLMNAMAPTTSHRKMT2A | |
| SCHEMBL29671336 | 0.82 | TSHR (0.73) | CDC25BMAPTTSHRMEN1KMT2A | |
| SCHEMBL2569253 | 0.82 | TSHR (0.73) | CDC25BMAPTTSHRMEN1KMT2A | |
| SCHEMBL28066258 | 0.81 | HTT (0.68) | CDC25BLMNAMAPTHPGDSKMT2A | |
| SCHEMBL28854104 | 0.80 | TSHR (0.49) | CDC25BLMNAMAPTTP53TSHR | |
| SCHEMBL1955830 | 0.80 | KDM4E (0.49) | CDC25BLMNAMAPTTSHRMEN1 | |
| SCHEMBL27793154 | 0.79 | CDC25B (0.52) | CDC25BLMNAMAPTTP53HPGDS | |
| SCHEMBL4502266 | 0.77 | TTR (0.53) | LMNAMAPTTSHRHTTCYP3A4 | |
| SCHEMBL27822304 | 0.77 | TSHR (0.53) | CDC25BMAPTTSHRMEN1KMT2A | |
| SCHEMBL27822305 | 0.77 | TSHR (0.53) | CDC25BTSHRMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105473548-A | Amide derivatives as lysophosphatidic acid receptor antagonists | TAKEDA PHARMACEUTICALS CO | 2016-04-06 | — | — | CN | disclosed |