O-Xylene

O-Xylene

SCHEMBL28066372

CCOC(C)OCC.Cc1ccccc1C

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.57
TSHR P16473 3/20 0.48
ACHE P22303 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.39
ESR1 P03372 1/20 0.38
SCN4A P35499 7/20 0.36
MAOA P21397 2/20 0.36
SCN1A P35498 2/20 0.36
SCN5A Q14524 2/20 0.36
SCN9A Q15858 2/20 0.36
CYP1A2 P05177 2/20 0.36
CYP3A4 P08684 2/20 0.36
CYP2D6 P10635 2/20 0.36
NFKB1 P19838 2/20 0.36
CYP2C9 P11712 1/20 0.36
KCNK3 O14649 1/20 0.36
CACNA1F O60840 1/20 0.36
KCNK2 O95069 1/20 0.36
GBA1 P04062 1/20 0.36
HTR2A P28223 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13086759 0.81 CYP1A2 (0.41) LMNATSHRL3MBTL1SCN4ACYP1A2
Biphenyl SCHEMBL3862996 0.81 LMNA (0.57) LMNAL3MBTL1CYP1A2CYP2C9MAPT
Biphenyl SCHEMBL8087383 0.79 LMNA (0.55) LMNAL3MBTL1CYP1A2CYP2C9MAPT
Tannin Pyrogallol SCHEMBL22288201 0.79 LMNA (0.55) LMNAL3MBTL1CYP1A2CYP2C9MAPT
Catechol SCHEMBL15986788 0.79 LMNA (0.55) LMNATSHRL3MBTL1CYP1A2CYP3A4
SCHEMBL4918898 0.79 LMNA (0.55) LMNATSHRL3MBTL1SLC6A4FFAR1
SCHEMBL449609 0.77 LMNA (0.52) LMNAL3MBTL1MAOASLC6A4KCNH2
Benzenethiol SCHEMBL4312885 0.77 LMNA (0.52) LMNAL3MBTL1MAOASLC6A4THRB
Chlorobenzene SCHEMBL108740 0.77 LMNA (0.52) LMNATSHRL3MBTL1SCN4ACYP1A2
Phenol SCHEMBL3315051 0.77 LMNA (0.52) LMNATSHRL3MBTL1ESR1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103702751-B Continuous catalyst regeneration in fluidized-bed reactor 阿克马法国公司 2016-10-12 CN claimed
CN-103702751-B Continuous catalyst regeneration in fluidized-bed reactor 阿克马法国公司 2016-10-12 CN disclosed
CN-103717301-B There is the plate-type reactor that original position is injected 阿克马法国公司 2016-06-22 CN disclosed