Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL28066833

C=CCC(C)(C)OC(=O)OC.N

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.35
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
MMP1 P03956 1/20 0.31
MMP9 P14780 1/20 0.31
MMP13 P45452 1/20 0.31
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18378114 0.87 ALDH1A1 (0.31) MAPTALDH1A1
SCHEMBL9541542 0.79 HTT (0.37) MAPTALDH1A1
SCHEMBL24131045 0.77
SCHEMBL9541538 0.77 ALDH1A1 (0.31) ALDH1A1
SCHEMBL5804465 0.77 GAA (0.41) MAPTALDH1A1
SCHEMBL9861013 0.75 HCAR2 (0.33) MAPTALDH1A1LMNA
SCHEMBL11602378 0.75 HTT (0.35) ALDH1A1LMNA
SCHEMBL3666505 0.75 TSHR (0.38) ALDH1A1
SCHEMBL9860291 0.75 HCAR2 (0.33) MAPTALDH1A1LMNA
SCHEMBL26247825 0.73 ALDH1A1 (0.34) ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109293517-A The method for preparing template 庄信万丰股份有限公司 2019-02-01 CN claimed
CN-109293517-A The method for preparing template 庄信万丰股份有限公司 2019-02-01 CN disclosed
CN-105612144-A Method for preparing template agent JOHNSON MATTHEY PLC 2016-05-25 CN disclosed