SCHEMBL28066870

SCHEMBL28066870

CCCc1c(OOc2cccc(C(C)C)c2CCC)cccc1C(C)C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.47
GABRG2 P18507 2/20 0.47
GABRB3 P28472 2/20 0.47
CYP1A2 P05177 2/20 0.38
CYP3A4 P08684 2/20 0.38
FAAH O00519 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
LMNA P02545 1/20 0.38
HPGD P15428 1/20 0.38
TSHR P16473 1/20 0.38
GABRB1 P18505 1/20 0.38
PTGS1 P23219 1/20 0.38
SLC6A2 P23975 1/20 0.38
HTR2C P28335 1/20 0.38
GABRA5 P31644 1/20 0.38
GABRA3 P34903 1/20 0.38
HTR2B P41595 1/20 0.38
GABRA2 P47869 1/20 0.38
GABRB2 P47870 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28020577 0.87 GABRA1 (0.40) GABRA1GABRG2GABRB3CYP1A2CYP3A4
SCHEMBL25108646 0.86 GABRA1 (0.44) GABRA1GABRG2GABRB3CYP1A2CYP3A4
SCHEMBL28458195 0.78 GABRA1 (0.38) GABRA1GABRG2GABRB3CYP1A2CYP3A4
SCHEMBL19289770 0.77 GABRA1 (0.50) GABRA1GABRG2GABRB3CYP1A2CYP3A4
SCHEMBL18629974 0.77 GABRA1 (0.50) GABRA1GABRG2GABRB3CYP1A2CYP3A4
SCHEMBL2318662 0.76 GABRA1 (0.46) GABRA1GABRG2GABRB3CYP1A2CYP3A4
SCHEMBL27929073 0.76 GABRA1 (0.53) GABRA1GABRG2GABRB3CYP1A2CYP3A4
SCHEMBL11981283 0.74 SMN1; SMN2 (0.44) CYP1A2LMNAGCGRL3MBTL1
SCHEMBL9178061 0.74 SMN1; SMN2 (0.44) CYP1A2LMNAGCGRL3MBTL1
SCHEMBL19289781 0.73 GABRA1 (0.46) GABRA1GABRG2GABRB3CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110312757-A Ethene-alpha-olefin copolymer-triallyl phosphate composition 陶氏环球技术有限责任公司 2019-10-08 CN claimed
CN-110248994-A Ethene-alpha-olefin copolymer-triallyl phosphate composition 陶氏环球技术有限责任公司 2019-09-17 CN claimed
CN-108884280-A Crosslinkable polymeric compositions with methyl scavengers and articles made therefrom 陶氏环球技术有限责任公司 2018-11-23 CN claimed
CN-105493202-B The degassing method of cross-linked power cable 陶氏环球技术有限责任公司 2018-10-12 CN disclosed
CN-104854185-B The polymerizable composition, polymerizable composition based on elastomer with amorphous silica filler 陶氏环球技术有限责任公司 2017-10-17 CN disclosed
CN-105493202-A Process for degassing crosslinked power cables DOW GLOBAL TECHNOLOGIES INC 2016-04-13 CN disclosed