⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27095789 | 0.79 | — | — | |
| SCHEMBL28228537 | 0.78 | — | — | |
| SCHEMBL4884653 | 0.77 | — | — | |
| SCHEMBL27988433 | 0.77 | — | — | |
| SCHEMBL29463955 | 0.71 | — | — | |
| SCHEMBL9279259 | 0.71 | — | — | |
| SCHEMBL9055158 | 0.71 | TSHR (0.33) | — | |
| SCHEMBL16589627 | 0.69 | — | — | |
| SCHEMBL9136351 | 0.69 | — | — | |
| SCHEMBL6844294 | 0.69 | CRBN (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108452378-B | 3D biological printing forming method | 中山大学附属第一医院 | 2020-10-23 | — | — | CN | claimed |
| CN-108310463-B | 3D printing biological ink and preparation method thereof | 中山大学附属第一医院 | 2020-10-23 | — | — | CN | disclosed |
| CN-108452378-B | 3D biological printing forming method | 中山大学附属第一医院 | 2020-10-23 | — | — | CN | disclosed |
| CN-105593215-B | 2, 4-or 4, 6-diaminopyrimidine compounds as IDH2 mutant inhibitors for the treatment of cancer | 安吉奥斯医药品有限公司 | 2019-01-15 | — | — | CN | disclosed |
| CN-105593215-A | 2, 4-or 4, 6-diaminopyrimidine compounds as IDH2 mutant inhibitors for the treatment of cancer | AGIOS PHARMACEUTICALS INC | 2016-05-18 | — | — | CN | disclosed |