⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28066932 | 0.77 | — | — | |
| SCHEMBL7540195 | 0.74 | — | — | |
| SCHEMBL27095789 | 0.74 | — | — | |
| SCHEMBL27988433 | 0.72 | — | — | |
| SCHEMBL9748590 | 0.72 | — | — | |
| SCHEMBL9279259 | 0.67 | — | — | |
| SCHEMBL9055158 | 0.67 | TSHR (0.33) | — | |
| SCHEMBL6541912 | 0.65 | — | — | |
| SCHEMBL16589627 | 0.65 | — | — | |
| SCHEMBL9136351 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080293660-A1 | CHEMICALLY-DEFINED NON-POLYMERIC VALENCY PLATFORM MOLECULES AND CONJUGATES THEREOF | LA JOLLA PHARMACEUTICAL COMPANY (US) | 2008-11-27 | — | — | US | disclosed |
| US-20070254851-A1 | Chemically-defined non-polymeric valency platform molecules and conjugates thereof | LA JOLLA PHARMACEUTICAL COMPANY | 2007-11-01 | — | — | US | disclosed |
| EP-1808183-A2 | Chemically-defined non-polymeric valency platform molecules and conjugates thereof | LA JOLLA PHARMACEUTICAL COMPANY (US) | 2007-07-18 | — | — | EP | disclosed |
| US-5633395-A | Chemically-defined non-polymeric valency platform molecules and conjugates thereof | LA JOLLA PHARMACEUTICAL COMPANY (US) | 1997-05-27 | — | — | US | disclosed |
| US-5606047-A | INCLUDES POLYNUCLEOTIDE DUPLEXES THAT HAVE SIGNIFICANT BINDING ACTIVITY FOR LUPUS ANTIBODIES | LA JOLLA PHARMACEUTICAL COMPANY (US) | 1997-02-25 | — | — | US | disclosed |
| US-5552391-A | Chemically-defined non-polymeric valency platform molecules and conjugates thereof | LA JOLLA PHARMACEUTICAL COMPANY (US) | 1996-09-03 | — | — | US | disclosed |
| EP-0642798-A2 | Chemically-defined non-polymeric valency platform molecules and conjugates thereof | LA JOLLA PHARMACEUTICAL COMPANY (CA) | 1995-03-15 | — | — | EP | disclosed |