Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.50 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.49 |
| ▸ | NAAA | Q02083 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29266760 | 1.00 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2KMT2AZDHHC7 | |
| SCHEMBL8662109 | 1.00 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2KMT2AZDHHC7 | |
| SCHEMBL12924885 | 1.00 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2KMT2AZDHHC7 | |
| SCHEMBL2288351 | 0.94 | KMT2A (0.53) | NPC1RAB9ASMN1; SMN2KMT2AASAH1 | |
| SCHEMBL29024338 | 0.89 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2ZDHHC7ASAH1 | |
| SCHEMBL11578611 | 0.89 | NPC1 (0.48) | NPC1RAB9ASMN1; SMN2ASAH1ALDH1A1 | |
| SCHEMBL14062067 | 0.89 | NPC1 (0.48) | NPC1RAB9ASMN1; SMN2ASAH1ALDH1A1 | |
| SCHEMBL4886826 | 0.88 | MMP8 (0.48) | NPC1RAB9ASMN1; SMN2ASAH1ALDH1A1 | |
| SCHEMBL28066882 | 0.88 | MMP8 (0.48) | NPC1RAB9ASMN1; SMN2ASAH1ALDH1A1 | |
| SCHEMBL8818975 | 0.88 | MMP8 (0.48) | NPC1RAB9ASMN1; SMN2ASAH1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103772536-B | A kind of catalytic component for vinyl polymerization or combined polymerization and catalyst thereof | SINOPEC CORP. (CN) | 2016-05-25 | — | — | CN | disclosed |