SCHEMBL28067161

SCHEMBL28067161

CC(C)(C)OC(=O)C1(NN)CC1

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.34
CYP4F2 P78329 1/20 0.31
CYP4A11 Q02928 1/20 0.31
MEN1 O00255 1/20 0.30
MAPK1 P28482 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5227332 0.92 NPSR1 (0.33) DGAT1CYP4F2CYP4A11
SCHEMBL5359677 0.90 MAPT (0.35) DGAT1
SCHEMBL16976214 0.81 DGAT1 (0.35) DGAT1CYP4F2CYP4A11MEN1MAPK1
SCHEMBL15461441 0.76 CA1 (0.33) DGAT1CYP4F2CYP4A11
SCHEMBL22529222 0.73 CYP4F2 (0.31) DGAT1CYP4F2CYP4A11MEN1KMT2A
SCHEMBL1696853 0.72 CA12 (0.41) DGAT1CYP4F2CYP4A11
SCHEMBL5098960 0.72 KMT2A (0.33) MEN1KMT2A
SCHEMBL3543225 0.72 KMT2A (0.33) MEN1KMT2A
SCHEMBL2312894 0.71 MAPK1 (0.34) DGAT1CYP4F2CYP4A11MAPK1
SCHEMBL15461474 0.71 NPSR1 (0.32) DGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105503647-A Preparation method of cyclopropylhydrazine hydrochloride SUZHOU HIGHFINE BIOTECH CO LTD 2016-04-20 CN claimed