SCHEMBL28067327

SCHEMBL28067327

C=C(C)C(=O)OCCCC(C)N=C=O

nearest known ligand 0.47

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.47
THRB P10828 1/20 0.41
POLB P06746 1/20 0.38
APEX1 P27695 1/20 0.38
HTT P42858 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
ALDH1A1 P00352 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20298227 0.90 TSHR (0.46) TSHRTHRBPOLBAPEX1HTT
SCHEMBL814048 0.80 TSHR (0.58) TSHRTHRBALDH1A1
SCHEMBL4102923 0.80 TSHR (0.46) TSHRTHRBPOLBAPEX1HTT
SCHEMBL383961 0.78 TSHR (0.59) TSHRTHRBPOLBAPEX1HTT
SCHEMBL1848844 0.78 THRB (0.43) TSHRTHRBPOLBAPEX1HTT
SCHEMBL1133048 0.76 TSHR (0.56) TSHRTHRBPOLBAPEX1HTT
SCHEMBL27464275 0.76 TSHR (0.56) TSHRTHRBPOLBAPEX1HTT
SCHEMBL28199930 0.76 TSHR (0.56) TSHRTHRBPOLBAPEX1HTT
SCHEMBL1502687 0.76 THRB (0.46) TSHRTHRBPOLBAPEX1HTT
SCHEMBL29085540 0.76 TSHR (0.51) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105732515-A Molecular synthesis method acrylic acid type functional monomer containing supermolecule quadrupolar hydrogen bond structure 新疆工程学院 2016-07-06 CN disclosed