Known targets — ChEMBL curated mechanism
FGFR1FGFR2FGFR3FGFR4FLT1FLT4KDRPDGFRAPDGFRB
The experimentally established mechanism targets of Ammonia Solution, Strong. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL126064 | 0.96 | — | — | |
| Ammonia Solution, Strong SCHEMBL677513 | 0.96 | — | — | |
| SCHEMBL27300926 | 0.96 | — | — | |
| Water SCHEMBL27813462 | 0.92 | — | — | |
| Methane SCHEMBL27711976 | 0.92 | — | — | |
| Methane SCHEMBL27711978 | 0.92 | — | — | |
| Hydrogen Sulfide SCHEMBL27262392 | 0.92 | — | — | |
| Ammonia Solution, Strong SCHEMBL676113 | 0.92 | — | — | |
| SCHEMBL27946637 | 0.92 | — | — | |
| Ammonia Solution, Strong SCHEMBL27762153 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106222993-A | The desizing processing method of pure cotton fabric | 常熟市华裕知识产权咨询服务有限公司 | 2016-12-14 | — | — | CN | claimed |
| CN-103897388-B | A kind of high-performance lower shrinkage release bearing nylon sleeve material and preparation method | 常州光洋轴承股份有限公司 | 2017-12-15 | — | — | CN | disclosed |
| CN-106380915-A | Cloth placement machine for industrial production | 常熟市诺信达机械设备有限公司 | 2017-02-08 | — | — | CN | disclosed |
| CN-106222997-A | The desizing processing method of victoria blended spinning fabric | 常熟市周行毛巾厂 | 2016-12-14 | — | — | CN | disclosed |
| CN-106222993-A | The desizing processing method of pure cotton fabric | 常熟市华裕知识产权咨询服务有限公司 | 2016-12-14 | — | — | CN | disclosed |
| CN-104531076-B | A kind of wet type water-retentivity dustfall agent | SHANDONG UNIV. OF SCIENCE & TECHNOLOGY (CN) | 2016-06-01 | — | — | CN | disclosed |
| CN-104531076-B | A kind of wet type water-retentivity dustfall agent | SHANDONG UNIV. OF SCIENCE & TECHNOLOGY (CN) | 2016-06-01 | — | — | CN | disclosed |
| CN-104531073-B | A kind of enhancing is to the dust-inhibitor of grit and coal body infiltration wetting effect | SHANDONG UNIV. OF SCIENCE & TECHNOLOGY (CN) | 2016-06-01 | — | — | CN | disclosed |
| CN-104531073-B | A kind of enhancing is to the dust-inhibitor of grit and coal body infiltration wetting effect | SHANDONG UNIV. OF SCIENCE & TECHNOLOGY (CN) | 2016-06-01 | — | — | CN | disclosed |