Known targets — ChEMBL curated mechanism
FGFR1FGFR2FGFR3FGFR4FLT1FLT4KDRPDGFRAPDGFRB
The experimentally established mechanism targets of Methane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL126064 | 0.96 | — | — | |
| Methane SCHEMBL1530927 | 0.96 | — | — | |
| SCHEMBL27300926 | 0.96 | — | — | |
| Water SCHEMBL27813462 | 0.92 | — | — | |
| Ammonia Solution, Strong SCHEMBL28067370 | 0.92 | — | — | |
| SCHEMBL27946637 | 0.92 | — | — | |
| Hydrogen Sulfide SCHEMBL27262392 | 0.92 | — | — | |
| Methane SCHEMBL27711976 | 0.92 | — | — | |
| SCHEMBL1904 | 0.91 | — | — | |
| SCHEMBL2058760 | 0.91 | CA5A (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101095647-A | Skin treatment article | JOHNSON & JOHNSON CONSUMER (US) | 2008-01-02 | — | — | CN | disclosed |