Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | OGG1 | O15527 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27704646 | 0.81 | ALDH1A1 (0.61) | MAOBCYP1A2CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL28782703 | 0.79 | MAOB (0.44) | MAOBCYP1A2CYP2D6CYP2C19ALDH1A1 | |
| Bromobenzene SCHEMBL27368728 | 0.77 | ALDH1A1 (0.50) | CYP1A2CYP2D6CYP2C19ALDH1A1TSHR | |
| Fluorobenzene SCHEMBL27339127 | 0.77 | TSHR (0.50) | ALDH1A1TSHRSLC6A4TP53 | |
| SCHEMBL27912054 | 0.77 | HDAC3 (0.42) | ALDH1A1TSHRSLC6A4TLR8LMNA | |
| Bromomethane SCHEMBL27848588 | 0.77 | ALDH1A1 (0.50) | MAOBCYP1A2CYP2D6ALDH1A1CTSL | |
| SCHEMBL6204215 | 0.77 | — | — | |
| SCHEMBL63128 | 0.77 | — | — | |
| SCHEMBL30437684 | 0.77 | — | — | |
| SCHEMBL18867939 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105492008-A | Novel compounds and compositions for inhibition of fasn | FORMA THERAPEUTICS INC | 2016-04-13 | — | — | CN | disclosed |