Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 8/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 8/20 | 0.44 |
| ▸ | KDM5B | Q9UGL1 | 8/20 | 0.44 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.43 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.39 |
| ▸ | KDM4A | O75164 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.35 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.35 |
| ▸ | OXTR | P30559 | 1/20 | 0.35 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22349328 | 0.82 | KDM5A (0.59) | KDM5AKDM4CKDM5BKDM2BKDM4A | |
| SCHEMBL17086621 | 0.80 | KDM4C (0.57) | KDM5AKDM4CKDM5BEGLN2KDM2B | |
| SCHEMBL15556900 | 0.74 | SLC11A2 (0.51) | KDM5AKDM4CKDM5BKDM2BKDM4A | |
| SCHEMBL15022263 | 0.74 | MAPK9 (0.54) | EGLN2MAPK9MAPK10CACNA1BMAPK8 | |
| SCHEMBL15022318 | 0.71 | MAPK9 (0.55) | EGLN2MAPK9MAPK10MAPK8 | |
| SCHEMBL15556530 | 0.70 | KDM4C (0.51) | KDM5AKDM4CKDM5BKDM2BKDM4A | |
| SCHEMBL21258294 | 0.69 | CYP1A2 (0.53) | EGLN2RAB9A | |
| SCHEMBL4906246 | 0.69 | KDM4E (0.50) | EGLN2RAB9A | |
| SCHEMBL15772406 | 0.68 | OXTR (0.43) | RAB9AOXTRAVPR1A | |
| SCHEMBL19378095 | 0.68 | KDM5A (0.65) | KDM5AKDM4CKDM5BMAPK9MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103159738-B | The heteroaryl aroma compounds of alkynyl bridging and application thereof | 上海泓博智源医药股份有限公司 | 2016-09-07 | — | — | CN | disclosed |