Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 6/20 | 0.76 |
| ▸ | TSHR | P16473 | 2/20 | 0.76 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.76 |
| ▸ | POLB | P06746 | 1/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.76 |
| ▸ | MAPT | P10636 | 1/20 | 0.76 |
| ▸ | RECQL | P46063 | 1/20 | 0.76 |
| ▸ | BLM | P54132 | 1/20 | 0.76 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.76 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.76 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.76 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.52 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.52 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 2/20 | 0.46 |
| ▸ | CES1 | P23141 | 2/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzamide SCHEMBL28196288 | 0.93 | PARP1 (0.80) | PARP1TSHRCYP2C19POLBCYP3A4 | |
| Benzamide SCHEMBL7094288 | 0.90 | PARP1 (0.84) | PARP1TSHRCYP2C19POLBCYP3A4 | |
| Benzamide SCHEMBL9551475 | 0.87 | PARP1 (0.89) | PARP1TSHRCYP2C19POLBCYP3A4 | |
| Benzamide SCHEMBL27624767 | 0.87 | PARP1 (0.89) | PARP1TSHRCYP2C19POLBCYP3A4 | |
| Benzamide SCHEMBL27506897 | 0.87 | PARP1 (0.89) | PARP1TSHRCYP2C19POLBCYP3A4 | |
| Benzamide SCHEMBL8697180 | 0.87 | PARP1 (0.89) | PARP1TSHRCYP2C19POLBCYP3A4 | |
| Benzamide SCHEMBL29618402 | 0.87 | — | — | |
| SCHEMBL21755166 | 0.87 | PARP1 (1.00) | PARP1TSHRCYP2C19POLBCYP3A4 | |
| Benzamide SCHEMBL16352 | 0.87 | — | — | |
| Benzamide SCHEMBL30112947 | 0.87 | PARP1 (1.00) | PARP1TSHRCYP2C19POLBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113527275-A | SKLB1039 compound and preparation method and application thereof | 成都师范学院 | 2021-10-22 | — | — | CN | disclosed |
| CN-105481793-A | Method for synthesis of 2-acetylphenothiazine from m-acetylchlorobenzene and benzamide | TAICANG YUNTONG BIOCHEMICAL ENG CO LTD | 2016-04-13 | — | — | CN | disclosed |