Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 6/20 | 1.00 |
| ▸ | TSHR | P16473 | 2/20 | 1.00 |
| ▸ | POLB | P06746 | 1/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 1/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 1/20 | 1.00 |
| ▸ | RECQL | P46063 | 1/20 | 1.00 |
| ▸ | BLM | P54132 | 1/20 | 1.00 |
| ▸ | PMP22 | Q01453 | 1/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 1.00 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.62 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.62 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.62 |
| ▸ | CES2 | O00748 | 2/20 | 0.58 |
| ▸ | CES1 | P23141 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | DAO | P14920 | 1/20 | 0.58 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzamide SCHEMBL30112947 | 1.00 | PARP1 (1.00) | PARP1TSHRPOLBCYP3A4MAPT | |
| Benzamide SCHEMBL11668921 | 1.00 | PARP1 (1.00) | PARP1TSHRPOLBCYP3A4MAPT | |
| Benzamide SCHEMBL6690447 | 1.00 | PARP1 (1.00) | PARP1TSHRPOLBCYP3A4MAPT | |
| Benzamide SCHEMBL1222101 | 1.00 | PARP1 (1.00) | PARP1TSHRPOLBCYP3A4MAPT | |
| Benzamide SCHEMBL16352 | 1.00 | — | — | |
| Benzamide SCHEMBL27963599 | 1.00 | PARP1 (1.00) | PARP1TSHRPOLBCYP3A4MAPT | |
| Benzamide SCHEMBL29618402 | 1.00 | — | — | |
| Benzamide SCHEMBL1332331 | 1.00 | — | — | |
| Benzamide SCHEMBL8961640 | 0.97 | PARP1 (0.94) | PARP1TSHRPOLBCYP3A4MAPT | |
| Benzamide SCHEMBL3864950 | 0.97 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230055040-A1 | Synthesis Of Benzodiazepine Derivatives | TRIO MEDICINES LIMITED (GB) | 2023-02-23 | — | — | US | disclosed |
| US-10570102-B2 | Synthesis of benzodiazepine derivatives | TRIO MEDICINES LIMITED (GB) | 2020-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10570102-B2 | Synthesis of benzodiazepine derivatives | GABRE, GABRA1, GABRA5 | PARP1 2657/4885TSHR 1097/4885POLB 2652/4885 |
| US-20230055040-A1 | Synthesis Of Benzodiazepine Derivatives | GABRE, GABRA1, GABRA5 | PARP1 2657/4885TSHR 1097/4885POLB 2652/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.