Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | MTOR | P42345 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.55 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.55 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.55 |
| ▸ | GMNN | O75496 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.55 |
| ▸ | THPO | P40225 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | HBB | P68871 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | PYGM | P11217 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL41572 | 0.93 | LMNA (0.62) | LMNAMTORALDH1A1TP53THRB | |
| SCHEMBL18512948 | 0.93 | LMNA (0.62) | LMNAMTORALDH1A1TP53THRB | |
| SCHEMBL14441083 | 0.93 | LMNA (0.62) | LMNAMTORALDH1A1TP53THRB | |
| SCHEMBL2584289 | 0.93 | LMNA (0.62) | LMNAMTORALDH1A1TP53THRB | |
| SCHEMBL6297856 | 0.93 | LMNA (0.62) | LMNAMTORALDH1A1TP53THRB | |
| SCHEMBL14929291 | 0.93 | LMNA (0.62) | LMNAMTORALDH1A1TP53THRB | |
| SCHEMBL5953706 | 0.93 | LMNA (0.62) | LMNAMTORALDH1A1TP53THRB | |
| SCHEMBL5953287 | 0.93 | LMNA (0.62) | LMNAMTORALDH1A1TP53THRB | |
| SCHEMBL5697581 | 0.93 | LMNA (0.62) | LMNAMTORALDH1A1TP53THRB | |
| SCHEMBL114751 | 0.93 | LMNA (0.62) | LMNAMTORALDH1A1TP53THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104011224-B | Methods and reagents for reducing non-specific amplification | HOFFMAN-LA ROCHE LTD. (CH) | 2016-05-25 | — | — | CN | disclosed |