Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 7/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 7/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28067700 | 0.79 | ELANE (0.39) | CHRNB2CHRNA4CHRNB4CHRNA3ELANE | |
| SCHEMBL28067746 | 0.77 | CHRNB2 (0.43) | CHRNB2CHRNA4CHRNB4CHRNA3HRH3 | |
| SCHEMBL28063442 | 0.73 | CHRNB2 (0.43) | CHRNB2CHRNA4CHRNB4CHRNA3HRH3 | |
| SCHEMBL12377900 | 0.71 | HRH3 (0.60) | CHRNB2CHRNA4CHRNB4CHRNA3HRH3 | |
| SCHEMBL17297914 | 0.70 | HRH3 (0.56) | CHRNB2CHRNA4CHRNB4CHRNA3HRH3 | |
| SCHEMBL6888784 | 0.67 | CHRNA7 (0.62) | CHRNB2CHRNA4HRH3DRD2CHRNA7 | |
| SCHEMBL29352658 | 0.67 | CHRNA7 (0.62) | CHRNB2CHRNA4HRH3DRD2CHRNA7 | |
| SCHEMBL17297909 | 0.67 | CHRNB2 (0.57) | CHRNB2CHRNA4CHRNB4CHRNA3HRH3 | |
| SCHEMBL17166193 | 0.66 | CHRNB2 (0.44) | CHRNB2CHRNA4CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL4760567 | 0.65 | HRH3 (0.57) | CHRNB2CHRNA4CHRNB4CHRNA3HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105744838-A | Heterocyclic compounds as pest control agents | 拜耳作物科学股份公司 | 2016-07-06 | — | — | CN | disclosed |