Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 18/20 | 0.41 |
| ▸ | HSD11B2 | P80365 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20129585 | 0.84 | GRM5 (0.41) | HSD11B1HSD11B2EPHX2 | |
| SCHEMBL3098791 | 0.83 | HSD11B1 (0.39) | HSD11B1HSD11B2EPHX2 | |
| SCHEMBL2450615 | 0.83 | HSD11B1 (0.39) | HSD11B1HSD11B2EPHX2 | |
| SCHEMBL19798632 | 0.83 | HSD11B1 (0.42) | HSD11B1HSD11B2EPHX2 | |
| SCHEMBL10234486 | 0.80 | HSD11B1 (0.40) | HSD11B1HSD11B2EPHX2 | |
| SCHEMBL12968026 | 0.80 | HSD11B1 (0.40) | HSD11B1HSD11B2EPHX2 | |
| SCHEMBL18157864 | 0.78 | HSD11B1 (0.42) | HSD11B1HSD11B2EPHX2 | |
| SCHEMBL19911078 | 0.77 | HSD11B1 (0.38) | HSD11B1HSD11B2EPHX2 | |
| SCHEMBL1772242 | 0.73 | CYP2C9 (0.46) | HSD11B1HSD11B2EPHX2 | |
| SCHEMBL12837800 | 0.73 | CYP2C9 (0.39) | HSD11B1HSD11B2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103242192-B | The inhibitor of 11-beta-hydroxysteroid dehydrogenase 1 type enzyme | ABBVIE INC. (US) | 2016-05-04 | — | — | CN | disclosed |