Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.56 |
| ▸ | METAP2 | P50579 | 2/20 | 0.56 |
| ▸ | METAP1 | P53582 | 2/20 | 0.56 |
| ▸ | BRD4 | O60885 | 1/20 | 0.56 |
| ▸ | HTR5A | P47898 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | CCR1 | P32246 | 1/20 | 0.47 |
| ▸ | CCR8 | P51685 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MMP14 | P50281 | 3/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2989427 | 0.86 | KDM4E (0.49) | KDM4EMAPTLMNAHSP90AA1METAP2 | |
| SCHEMBL28509226 | 0.84 | KDM4E (0.58) | KDM4EMAPTLMNAHSP90AA1METAP2 | |
| SCHEMBL10157968 | 0.82 | KDM4E (0.56) | KDM4EMAPTLMNAHSP90AA1METAP2 | |
| SCHEMBL2320450 | 0.79 | KDM4E (0.57) | KDM4EMAPTLMNAHSP90AA1METAP2 | |
| SCHEMBL28067774 | 0.79 | HTT (0.56) | KDM4EMAPTLMNAHSP90AA1ALDH1A1 | |
| SCHEMBL196536 | 0.78 | KDM4E (0.70) | KDM4EMAPTLMNAHSP90AA1METAP2 | |
| SCHEMBL10415547 | 0.77 | MAPT (0.66) | KDM4EMAPTLMNAHSP90AA1METAP2 | |
| Hydrochloric Acid SCHEMBL11663296 | 0.76 | MAPT (0.64) | KDM4EMAPTLMNAHSP90AA1METAP2 | |
| SCHEMBL31434767 | 0.76 | HSP90AA1 (0.61) | KDM4EMAPTLMNAHSP90AA1METAP2 | |
| SCHEMBL2423195 | 0.76 | HSP90AA1 (0.61) | KDM4EMAPTLMNAHSP90AA1METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105601565-A | Method for preparing polyisocyanate containing biuret structure with stable storage | WANHUA CHEMICAL GROUP CO LTD | 2016-05-25 | — | — | CN | disclosed |