Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.56 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.56 |
| ▸ | COPS5 | Q92905 | 2/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | CCR1 | P32246 | 3/20 | 0.47 |
| ▸ | CCR8 | P51685 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | CCR5 | P51681 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10157939 | 0.84 | HTT (0.58) | HTTPSMD14COPS5SLC6A2CCR1 | |
| SCHEMBL28067792 | 0.79 | KDM4E (0.56) | HTTSLC6A2CCR1CCR8L3MBTL1 | |
| SCHEMBL812451 | 0.78 | HTT (0.70) | HTTPSMD14COPS5SLC6A2CCR1 | |
| SCHEMBL8342933 | 0.78 | PAX8 (0.59) | HTTPSMD14COPS5SLC6A2CCR1 | |
| SCHEMBL17936470 | 0.77 | HTT (0.50) | HTTPSMD14COPS5SLC6A2CCR1 | |
| SCHEMBL20064289 | 0.77 | HTT (0.50) | HTTPSMD14COPS5SLC6A2CCR1 | |
| SCHEMBL28028252 | 0.76 | MEN1 (0.54) | HTTPSMD14COPS5SLC6A2CCR1 | |
| SCHEMBL11973402 | 0.76 | PSMD14 (0.61) | HTTPSMD14COPS5SLC6A2CCR1 | |
| SCHEMBL29800867 | 0.76 | PSMD14 (0.61) | HTTPSMD14COPS5SLC6A2CCR1 | |
| SCHEMBL19494146 | 0.74 | HTT (0.51) | HTTPSMD14COPS5SLC6A2CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105601565-A | Method for preparing polyisocyanate containing biuret structure with stable storage | WANHUA CHEMICAL GROUP CO LTD | 2016-05-25 | — | — | CN | claimed |
| CN-105601565-B | A kind of preparation method of the polyisocyanates of the biuret-containing structure of stable storage | 万华化学集团股份有限公司 | 2018-05-15 | — | — | CN | disclosed |
| CN-105601565-A | Method for preparing polyisocyanate containing biuret structure with stable storage | WANHUA CHEMICAL GROUP CO LTD | 2016-05-25 | — | — | CN | disclosed |