Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.49 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13613722 | 1.00 | SPHK1 (0.49) | SPHK1HSD11B2BRD4CHRM2CHRM1 | |
| SCHEMBL16325799 | 1.00 | SPHK1 (0.49) | SPHK1HSD11B2BRD4CHRM2CHRM1 | |
| SCHEMBL4594516 | 0.90 | SPHK1 (0.48) | SPHK1HSD11B2BRD4CHRM2CHRM1 | |
| SCHEMBL1863728 | 0.87 | SPHK1 (0.46) | SPHK1HSD11B2BRD4CHRM2CHRM1 | |
| SCHEMBL14489664 | 0.87 | SPHK1 (0.46) | SPHK1HSD11B2BRD4CHRM2CHRM1 | |
| SCHEMBL1863729 | 0.87 | SPHK1 (0.46) | SPHK1HSD11B2BRD4CHRM2CHRM1 | |
| SCHEMBL6125269 | 0.87 | SPHK1 (0.53) | SPHK1HSD11B2BRD4CHRM2CHRM1 | |
| SCHEMBL20621505 | 0.87 | SPHK1 (0.53) | SPHK1HSD11B2BRD4CHRM2CHRM1 | |
| SCHEMBL1067809 | 0.87 | SPHK1 (0.50) | SPHK1HSD11B2BRD4CHRM2CHRM1 | |
| SCHEMBL1526136 | 0.87 | SPHK1 (0.50) | SPHK1HSD11B2BRD4CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105705500-A | Amide compounds for the treatment of HIV | 吉利德科学公司 | 2016-06-22 | — | — | CN | disclosed |