Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487429 | 0.93 | KMT2A (0.58) | KMT2APTGS1PTGS2LTA4HCYP3A4 | |
| SCHEMBL12067910 | 0.93 | KMT2A (0.58) | KMT2APTGS1PTGS2LTA4HCYP3A4 | |
| SCHEMBL4731036 | 0.93 | KMT2A (0.58) | KMT2APTGS1PTGS2LTA4HCYP3A4 | |
| Hydrochloric Acid SCHEMBL27549891 | 0.92 | KMT2A (0.56) | KMT2APTGS1PTGS2LTA4HCYP3A4 | |
| Ammonia Solution, Strong SCHEMBL6349111 | 0.92 | KMT2A (0.56) | KMT2APTGS1PTGS2LTA4HCYP3A4 | |
| Hydrochloric Acid SCHEMBL6427164 | 0.92 | KMT2A (0.56) | KMT2APTGS1PTGS2LTA4HCYP3A4 | |
| Acetic Acid SCHEMBL27782195 | 0.90 | KMT2A (0.55) | KMT2APTGS1PTGS2LTA4HCYP3A4 | |
| Acetic Acid SCHEMBL487399 | 0.90 | KMT2A (0.55) | KMT2APTGS1PTGS2LTA4HCYP3A4 | |
| SCHEMBL27565933 | 0.80 | DPP4 (0.43) | KMT2ACYP1A2CYP2D6MAPK1DPP4 | |
| Mandelic Acid, Methyl Ester SCHEMBL30951860 | 0.80 | KMT2A (0.63) | KMT2APTGS1PTGS2CYP2D6MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2108014-A1 | METHOD OF PREPARING DOCETAXEL AND INTERMEDIATES USED THEREIN | Hanmi Pharm. Co., Ltd. (KR) | 2009-10-14 | — | — | EP | claimed |
| WO-2008072849-A1 | METHOD OF PREPARING DOCETAXEL AND INTERMEDIATES USED THEREIN | HANMI PHARM. CO., LTD. (KR) | 2008-06-19 | — | — | WO | claimed |
| US-20100099896-A1 | METHOD OF PREPARING DOCETAXEL AND INTERMEDIATES USED THEREIN | HANMI PHARM. CO. LTD (KR) | 2010-04-22 | — | — | US | disclosed |
| EP-2108014-A1 | METHOD OF PREPARING DOCETAXEL AND INTERMEDIATES USED THEREIN | Hanmi Pharm. Co., Ltd. (KR) | 2009-10-14 | — | — | EP | disclosed |
| WO-2008072849-A1 | METHOD OF PREPARING DOCETAXEL AND INTERMEDIATES USED THEREIN | HANMI PHARM. CO., LTD. (KR) | 2008-06-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099896-A1 | METHOD OF PREPARING DOCETAXEL AND INTERMEDIATES USED THEREIN | MCL1, DPYD, THPO | KMT2A 3620/4885PTGS1 2625/4885PTGS2 2558/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.