Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12067910 | 1.00 | KMT2A (0.58) | KMT2ALTA4HDPP4CYP3A4CYP1A2 | |
| SCHEMBL4731036 | 1.00 | KMT2A (0.58) | KMT2ALTA4HDPP4CYP3A4CYP1A2 | |
| Hydrochloric Acid SCHEMBL6427164 | 0.98 | KMT2A (0.56) | KMT2ALTA4HDPP4CYP3A4CYP1A2 | |
| Hydrochloric Acid SCHEMBL27549891 | 0.98 | KMT2A (0.56) | KMT2ALTA4HDPP4CYP3A4CYP1A2 | |
| Ammonia Solution, Strong SCHEMBL6349111 | 0.98 | KMT2A (0.56) | KMT2ALTA4HDPP4CYP3A4CYP1A2 | |
| Acetic Acid SCHEMBL27782195 | 0.96 | KMT2A (0.55) | KMT2ALTA4HDPP4CYP3A4CYP1A2 | |
| Acetic Acid SCHEMBL487399 | 0.96 | KMT2A (0.55) | KMT2ALTA4HDPP4CYP3A4CYP1A2 | |
| Formic Acid SCHEMBL2806812 | 0.93 | KMT2A (0.56) | KMT2ALTA4HDPP4CYP3A4CYP1A2 | |
| SCHEMBL4884767 | 0.82 | MMP8 (0.51) | KMT2ADPP4TSHRMEN1 | |
| SCHEMBL6156033 | 0.82 | MMP8 (0.51) | KMT2ADPP4TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014099850-A1 | FACTOR IXa 318R/A MUTANT | MERCK SHARP & DOHME CORP. (US) | 2014-06-26 | — | — | WO | disclosed |
| US-8106231-B2 | Process for the preparation of (2R,3S)-3-phenylisoserine methyl ester acetate salt | INDENA S.P.A. (IT) | 2012-01-31 | — | — | US | disclosed |
| US-8106231-B2 | Process for the preparation of (2R,3S)-3-phenylisoserine methyl ester acetate salt | INDENA S.P.A. (IT) | 2012-01-31 | — | — | US | disclosed |
| US-8106231-B2 | Process for the preparation of (2R,3S)-3-phenylisoserine methyl ester acetate salt | INDENA S.P.A. (IT) | 2012-01-31 | — | — | US | disclosed |
| US-20100168460-A1 | PROCESS FOR THE PREPARATION OF (2R,3S)-3-PHENYLISOSERINE METHYL ESTER ACETATE SALT | INDENA S.P.A. (IT) | 2010-07-01 | — | — | US | disclosed |
| US-20100168460-A1 | PROCESS FOR THE PREPARATION OF (2R,3S)-3-PHENYLISOSERINE METHYL ESTER ACETATE SALT | INDENA S.P.A. (IT) | 2010-07-01 | — | — | US | disclosed |
| US-20100168460-A1 | PROCESS FOR THE PREPARATION OF (2R,3S)-3-PHENYLISOSERINE METHYL ESTER ACETATE SALT | INDENA S.P.A. (IT) | 2010-07-01 | — | — | US | disclosed |
| US-20100099896-A1 | METHOD OF PREPARING DOCETAXEL AND INTERMEDIATES USED THEREIN | HANMI PHARM. CO. LTD (KR) | 2010-04-22 | — | — | US | disclosed |
| EP-1961735-B1 | Process for the preparation of (2r,3s)-3-phenylisoserine methyl ester acetate salt | INDENA SPA (IT) | 2009-11-18 | — | — | EP | disclosed |
| EP-1961735-B1 | Process for the preparation of (2r,3s)-3-phenylisoserine methyl ester acetate salt | INDENA SPA (IT) | 2009-11-18 | — | — | EP | disclosed |
| EP-0912504-A1 | PROCESS TO PREPARE TAXOL | PHARMACIA & UPJOHN COMPANY (US) | 1999-05-06 | — | — | EP | disclosed |
| US-5821363-A | Antineoplastic use and pharmaceutical compositions containing them | PHARMACIA & UPJOHN COMPANY (US) | 1998-10-13 | — | — | US | disclosed |
| WO-1997042167-A1 | PROCESS TO PREPARE TAXOL | PHARMACIA & UPJOHN COMPANY (US) | 1997-11-13 | — | — | WO | disclosed |
| EP-0741716-A1 | DELTA 12,13 -ISO-TAXOL ANALOGS, ANTINEOPLASTIC USE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | PHARMACIA & UPJOHN COMPANY (US) | 1996-11-13 | — | — | EP | disclosed |
| US-5556878-A | Δ6,7 -taxols antineoplatic use and pharmaceutical compositions containing them | THE UPJOHN COMPANY (US) | 1996-09-17 | — | — | US | disclosed |
| EP-0703909-A1 | $g(D)?6,7 -TAXOLS ANTINEOPLASTIC USE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | PHARMACIA & UPJOHN COMPANY (US) | 1996-04-03 | — | — | EP | disclosed |
| EP-0674630-A1 | 7-HALO- AND 7$g(b),8$g(b)-METHANO-TAXOLS, ANTINEOPLASTIC USE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | PHARMACIA & UPJOHN COMPANY (US) | 1995-10-04 | — | — | EP | disclosed |
| WO-1995020582-A1 | Δ12,13-ISO-TAXOL ANALOGS, ANTINEOPLASTIC USE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | PHARMACIA & UPJOHN COMPANY (US) | 1995-08-03 | — | — | WO | disclosed |
| WO-1994029288-A1 | Δ6,7-TAXOLS ANTINEOPLASTIC USE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | THE UPJOHN COMPANY (US) | 1994-12-22 | — | — | WO | disclosed |
| WO-1994013655-A1 | 7-HALO- AND 7β,8β-METHANO-TAXOLS, ANTINEOPLASTIC USE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | THE UPJOHN COMPANY (US) | 1994-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099896-A1 | METHOD OF PREPARING DOCETAXEL AND INTERMEDIATES USED THEREIN | MCL1, DPYD, THPO | KMT2A 3620/4885LTA4H 4029/4885DPP4 4062/4885 |
| US-20100168460-A1 | PROCESS FOR THE PREPARATION OF (2R,3S)-3-PHENYLISOSERINE METHYL ESTER ACETATE SALT | SPTSSB, SRR, MTAP | KMT2A 1909/4885LTA4H 4483/4885DPP4 3269/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.