Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ENO1 | P06733 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27993431 | 1.00 | HTT (0.37) | HTTENO1L3MBTL1POLBDPP4 | |
| SCHEMBL29286313 | 1.00 | HTT (0.37) | HTTENO1L3MBTL1POLBDPP4 | |
| SCHEMBL27655705 | 0.95 | HTT (0.36) | HTTENO1 | |
| SCHEMBL27812245 | 0.95 | HTT (0.36) | HTTENO1 | |
| SCHEMBL27851530 | 0.95 | HTT (0.36) | HTTENO1 | |
| SCHEMBL29290181 | 0.88 | ENO1 (0.33) | ENO1L3MBTL1POLB | |
| SCHEMBL28758510 | 0.85 | ENO1 (0.35) | ENO1L3MBTL1POLB | |
| SCHEMBL27886924 | 0.85 | ENO1 (0.35) | ENO1L3MBTL1POLB | |
| SCHEMBL27625590 | 0.85 | ENO1 (0.35) | ENO1L3MBTL1POLB | |
| SCHEMBL28210802 | 0.84 | ENO1 (0.35) | ENO1L3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109153681-A | Novel 5H-pyrrolo [2, 3-d ] pyrimidin-6 (7H) -one derivatives | 大鹏药品工业株式会社 | 2019-01-04 | — | — | CN | disclosed |
| CN-109069489-A | Diamino-alkylamino linked arylsulfonamide compounds having selective activity for voltage-gated sodium channels | 默沙东公司 | 2018-12-21 | — | — | CN | disclosed |
| CN-109071563-A | Inhibitors of bruton's tyrosine kinase and methods of use thereof | 詹森药业有限公司 | 2018-12-21 | — | — | CN | disclosed |
| CN-105732636-A | Hetero-aromatic compounds and applications thereof in pharmacy | 广东东阳光药业有限公司 | 2016-07-06 | — | — | CN | disclosed |