Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | VNN1 | O95497 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27861569 | 0.88 | CTDSP1 (0.37) | CTDSP1CYP1A2VNN1P2RX7HRH1 | |
| SCHEMBL28021265 | 0.81 | CTDSP1 (0.41) | CTDSP1CYP1A2VNN1P2RX7BRD4 | |
| Hydrochloric Acid SCHEMBL27823343 | 0.80 | CTDSP1 (0.41) | CTDSP1CYP1A2VNN1P2RX7BRD4 | |
| SCHEMBL27558627 | 0.79 | — | — | |
| SCHEMBL5252807 | 0.76 | HRH1 (0.50) | CYP1A2HRH1 | |
| SCHEMBL3079246 | 0.76 | CYP1A2 (0.47) | CTDSP1CYP1A2VNN1P2RX7BRD4 | |
| SCHEMBL30481580 | 0.76 | CTDSP1 (0.42) | CTDSP1CYP1A2VNN1P2RX7BRD4 | |
| SCHEMBL28299484 | 0.76 | CTDSP1 (0.42) | CTDSP1CYP1A2VNN1P2RX7BRD4 | |
| Bromide SCHEMBL28768599 | 0.75 | CA12 (0.49) | CYP1A2HRH1 | |
| Hydrochloric Acid SCHEMBL27562976 | 0.75 | CA12 (0.49) | CYP1A2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106831782-A | The synthetic method of 6 chlorine imidazos [1,2 b] formic acid of pyridazine 3 | 山东友帮生化科技有限公司 | 2017-06-13 | — | — | CN | claimed |
| CN-101868458-B | Isoxazolo-pyridazine derivatives | HOFFMANN LA ROCHE | 2012-11-28 | — | — | CN | claimed |
| CN-101868458-A | Isoxazolo-pyridazine derivatives | HOFFMANN LA ROCHE | 2010-10-20 | — | — | CN | claimed |
| CN-110317213-A | The huge ring of the diaryl of regulator as protein kinase | 特普医药公司 | 2019-10-11 | — | — | CN | disclosed |
| CN-110317214-A | The huge ring of the diaryl of regulator as protein kinase | 特普医药公司 | 2019-10-11 | — | — | CN | disclosed |
| CN-110191887-A | The Imidazopyridazine regulator of IL-12, IL-23 and/or IFN-α | 百时美施贵宝公司 | 2019-08-30 | — | — | CN | disclosed |
| CN-110099901-A | Pyrazolo [3,4-b] pyridine and imidazo [1,5-b] pyridazine as PDE1 inhibitor | H.隆德贝克有限公司 | 2019-08-06 | — | — | CN | disclosed |
| CN-106170289-B | Diaryl macrocycles as modulators of protein kinases | 特普医药公司 | 2019-07-23 | — | — | CN | disclosed |
| CN-110036015-A | It can be used as the Imidazopyridazine compounds of the regulator of IL-12, IL-23 and/or IFN α response | 百时美施贵宝公司 | 2019-07-19 | — | — | CN | disclosed |
| CN-109923113-A | novel isoxazolyl ether derivatives as GABA A α 5 PAM | 豪夫迈·罗氏有限公司 | 2019-06-21 | — | — | CN | disclosed |
| CN-106459027-B | 6-substituted-3H-1, 3-benzothiazol-2-one compounds as TARP-gamma 8 dependent AMPA receptor antagonists | 伊莱利利公司 | 2019-04-02 | — | — | CN | disclosed |
| CN-105658640-A | Alkynyl alcohols and methods of use | 豪夫迈·罗氏有限公司 | 2016-06-08 | — | — | CN | disclosed |
| CN-101981033-B | Substituted imidazopyridazines useful as kinase inhibitors | BRISTOL MYERS SQUIBB CO | 2015-02-04 | — | — | CN | disclosed |
| CN-101868458-B | Isoxazolo-pyridazine derivatives | HOFFMANN LA ROCHE | 2012-11-28 | — | — | CN | disclosed |
| CN-102395585-A | Heteroaryls and their use as pi3k inhibitors | MILLENNIUM PHARM INC | 2012-03-28 | — | — | CN | disclosed |
| CN-101981033-A | Substituted imidazopyridazines useful as kinase inhibitors | BRISTOL MYERS SQUIBB CO | 2011-02-23 | — | — | CN | disclosed |
| CN-101868458-A | Isoxazolo-pyridazine derivatives | HOFFMANN LA ROCHE | 2010-10-20 | — | — | CN | disclosed |
| CN-100349895-C | Pyrrolopyridazine derivatives | ASTELLAS PHARMA INC (JP) | 2007-11-21 | — | — | CN | disclosed |
| CN-1759117-A | Pyrrolopyridazine derivatives | ASTELLAS PHARMA INC (JP) | 2006-04-12 | — | — | CN | disclosed |
| CN-1229408-A | Dihydroindole derivatives useful as 5-HT-2C receptor antagonists | SMITHKLINE BEECHAM PLC (GB) | 1999-09-22 | — | — | CN | disclosed |