Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 3/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GOT1 | P17174 | 1/20 | 0.32 |
| ▸ | VNN1 | O95497 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30481580 | 1.00 | CTDSP1 (0.42) | CTDSP1CYP1A2P2RX7HRH1CHRM1 | |
| SCHEMBL3079246 | 0.80 | CYP1A2 (0.47) | CTDSP1CYP1A2P2RX7HRH1CHRM1 | |
| SCHEMBL3150298 | 0.79 | — | — | |
| SCHEMBL3240853 | 0.77 | — | — | |
| SCHEMBL31356502 | 0.77 | — | — | |
| SCHEMBL18854185 | 0.76 | CYP1A2 (0.44) | CTDSP1CYP1A2P2RX7HRH1CHRM1 | |
| SCHEMBL14167085 | 0.76 | CTDSP1 (0.42) | CTDSP1CYP1A2P2RX7HRH1CHRM1 | |
| SCHEMBL31571547 | 0.76 | KCNA3 (0.47) | CYP1A2VNN1KCNH2ALDH1A1 | |
| SCHEMBL28068540 | 0.76 | CTDSP1 (0.43) | CTDSP1CYP1A2P2RX7HRH1CHRM1 | |
| SCHEMBL12079657 | 0.74 | SCN8A (0.46) | CTDSP1CYP1A2VNN1KMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109790143-A | Amine-linked C for target protein degradation3-glutarimide solution stator body | C4医药公司 | 2019-05-21 | — | — | CN | disclosed |