Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.52 |
| ▸ | NOS1 | P29475 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.43 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.43 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3319825 | 0.94 | MAPT (0.55) | NOS3NOS1MAPTGAAHDAC1 | |
| SCHEMBL26546702 | 0.78 | NPC1 (0.62) | MAPTGAAHDAC1HDAC6HTT | |
| SCHEMBL8383436 | 0.78 | NOS3 (0.51) | NOS3NOS1MAPTGAAHDAC1 | |
| SCHEMBL2287753 | 0.78 | MAPT (0.55) | NOS3NOS1MAPTGAAHDAC1 | |
| SCHEMBL31010071 | 0.78 | KAT7 (0.50) | NOS3NOS1MAPTGAAHDAC1 | |
| SCHEMBL30046633 | 0.77 | MEN1 (0.59) | MAPTGAAHTTUSP2PDE4B | |
| SCHEMBL5792386 | 0.77 | MEN1 (0.59) | MAPTGAAHTTUSP2PDE4B | |
| SCHEMBL301503 | 0.77 | GAA (0.62) | NOS3NOS1MAPTGAAHDAC1 | |
| SCHEMBL7627846 | 0.77 | MAPT (0.62) | NOS3NOS1MAPTGAAHDAC1 | |
| SCHEMBL7629829 | 0.76 | MAPT (0.54) | NOS3NOS1MAPTGAAHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113620878-B | Ni metal-organic framework material and preparation method and application thereof | 山西大学 | 2023-01-31 | — | — | CN | claimed |
| CN-105753845-A | Low-symmetry tetradentate pyrazole ligand Ni based metal-organic framework material and preparation method thereof | 北京工业大学 | 2016-07-13 | — | — | CN | claimed |
| CN-113620878-B | Ni metal-organic framework material and preparation method and application thereof | 山西大学 | 2023-01-31 | — | — | CN | disclosed |
| CN-113620878-A | Ni metal-organic framework material and preparation method and application thereof | 山西大学 | 2021-11-09 | — | — | CN | disclosed |
| CN-105753845-B | A kind of metal-organic framework materials and preparation method thereof based on low symmetrical four teeth Pyrazole Ligands Ni | 北京工业大学 | 2018-07-31 | — | — | CN | disclosed |
| CN-105753845-A | Low-symmetry tetradentate pyrazole ligand Ni based metal-organic framework material and preparation method thereof | 北京工业大学 | 2016-07-13 | — | — | CN | disclosed |