SCHEMBL28068681

SCHEMBL28068681

[N-]=[N+]=NC1C=COCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17696607 0.70
SCHEMBL13445267 0.64
SCHEMBL27839089 0.63
SCHEMBL20017367 0.61
SCHEMBL30148857 0.58
SCHEMBL27763908 0.58
SCHEMBL5973258 0.58
SCHEMBL320080 0.58
SCHEMBL17593302 0.58
SCHEMBL682533 0.58

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103687860-B As P2X7Heterocyclic amide derivatives of receptor antagonists 埃科特莱茵药品有限公司 2016-06-08 CN disclosed
CN-101203516-A Purine and imidazopyridine derivatives for immunosuppression PHARMACOPEIA INC (US) 2008-06-18 CN disclosed