Pivalate

Pivalate

SCHEMBL28069023

C=O.CC(C)(C)C(=O)O.CC(C)(C)C(=O)O

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.53
TSHR P16473 3/20 0.53
CYP2D6 P10635 1/20 0.40
CYP2C19 P33261 1/20 0.40
HIF1A Q16665 1/20 0.40
TET2 Q6N021 1/20 0.38
TP53 P04637 1/20 0.38
FFAR3 O14843 1/20 0.36
LCK P06239 1/20 0.36
FYN P06241 1/20 0.36
HMGCR P04035 1/20 0.35
CHRM1 P11229 1/20 0.35
TBXA2R P21731 1/20 0.35
ADRA1A P35348 1/20 0.35
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31
GGT1 P19440 1/20 0.31
MEN1 O00255 1/20 0.31
CYP1A2 P05177 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pivalate SCHEMBL27519097 0.92
Pivalate SCHEMBL4318862 0.91
Pivalate SCHEMBL3613 0.91
Pivalate SCHEMBL5116637 0.91 TSHR (0.61) ALDH1A1TSHRCYP2D6CYP2C19HIF1A
Pivalate SCHEMBL332912 0.91 TSHR (0.61) ALDH1A1TSHRCYP2D6CYP2C19HIF1A
Pivalate SCHEMBL25209317 0.87
Pivalate SCHEMBL15771206 0.87
Pivalate SCHEMBL6511203 0.87
Pivalate SCHEMBL10822159 0.87
Pivalate SCHEMBL1685641 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105622625-A Synthesis method of benzopyrone and imidazopyridine compound UNIV HENAN NORMAL 2016-06-01 CN disclosed