Caprolactam

Caprolactam

SCHEMBL28069032

O=C1CCCCCN1.O=S(=O)(O)OS(=O)(=O)O

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 3/20 0.61
FKBP5 Q13451 1/20 0.61
OR51E2 Q9H255 1/20 0.52
KDM4E B2RXH2 2/20 0.44
GAA P10253 1/20 0.44
POLB P06746 1/20 0.44
MERTK Q12866 1/20 0.32
CTSD P07339 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Pyrrolidone SCHEMBL27698785 0.92 OR51E2 (0.62) CRBNFKBP5OR51E2KDM4EGAA
Sulfuric Acid SCHEMBL28455727 0.88 CRBN (0.73) CRBNFKBP5OR51E2KDM4EGAA
Caprolactam SCHEMBL1521129 0.88 CRBN (0.73) CRBNFKBP5OR51E2KDM4EGAA
Caprolactam SCHEMBL27970597 0.86 CRBN (0.70) CRBNFKBP5OR51E2KDM4EGAA
Caprolactam SCHEMBL27823099 0.86 CRBN (0.70) CRBNFKBP5OR51E2KDM4EGAA
Sulfuric Acid SCHEMBL30278662 0.86 CRBN (0.76) CRBNFKBP5OR51E2KDM4EGAA
Caprolactam SCHEMBL28831685 0.84 CRBN (0.67) CRBNFKBP5OR51E2KDM4EGAA
Caprolactam SCHEMBL27842057 0.84 CRBN (0.67) CRBNFKBP5OR51E2KDM4EGAA
Caprolactam SCHEMBL17238720 0.82 CRBN (0.64) CRBNFKBP5OR51E2KDM4EGAA
Caprolactam SCHEMBL28301539 0.81 CRBN (0.84) CRBNFKBP5OR51E2KDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104341424-B The method of ionic liquid-catalyzed nitrated synthesis TNAD 南京理工大学 2016-07-06 CN claimed
CN-105315211-B The method that high concentration fuming sulfuric acid catalysis of pimelinketone oxime prepares caprolactam 中国石油化工股份有限公司 2018-01-09 CN disclosed
CN-105669342-B A kind of method that p-tert-butyltoluene is synthesized using caprolactam class ionic liquid as catalyst 中国石油大学(华东) 2017-12-19 CN disclosed
CN-104341424-B The method of ionic liquid-catalyzed nitrated synthesis TNAD 南京理工大学 2016-07-06 CN disclosed
CN-105669342-A Method of synthesizing p-tert-butyl toluene with caprolactam ionic liquid as catalyst 中国石油大学(华东) 2016-06-15 CN disclosed