Stearic Acid

Stearic Acid

SCHEMBL28069036

CC(N)=O.CCCCCCCCCCCCCCCCCC(=O)O.CCCCN(CCCC)C(C)C(N)=O

nearest known ligand 0.52

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Known targets — ChEMBL curated mechanism

rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 7/20 0.52
PPARG P37231 7/20 0.52
PPARD Q03181 7/20 0.52
PPARA Q07869 7/20 0.52
HDAC11 Q96DB2 5/20 0.52
TSHR P16473 4/20 0.52
PTPN1 P18031 3/20 0.52
ALDH1A1 P00352 2/20 0.52
TLR2 O60603 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
FABP4 P15090 2/20 0.52
KMT2A Q03164 2/20 0.52
FFAR1 O14842 2/20 0.52
FFAR4 Q5NUL3 2/20 0.52
ALOX15 P16050 2/20 0.52
HSD17B10 Q99714 2/20 0.52
SLC22A6 Q4U2R8 1/20 0.52
SLC22A8 Q8TCC7 1/20 0.52
MEN1 O00255 1/20 0.52
ESR1 P03372 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Palmitic Acid SCHEMBL28958123 0.91 GPR84 (0.55) GPR84PPARGPPARDPPARAHDAC11
Stearic Acid SCHEMBL28069035 0.91 GPR84 (0.55) GPR84PPARGPPARDPPARAHDAC11
Stearic Acid SCHEMBL28068986 0.89 GPR84 (0.53) GPR84PPARGPPARDPPARAHDAC11
Palmitic Acid SCHEMBL28069060 0.89 GPR84 (0.53) GPR84PPARGPPARDPPARAHDAC11
Stearic Acid SCHEMBL27729832 0.86 GPR84 (0.57) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL28847191 0.83 CA1 (0.42) ALDH1A1KMT2AMEN1LMNACYP1A2
Behenic Acid SCHEMBL28997831 0.81 GPR84 (0.59) GPR84PPARGPPARDPPARAHDAC11
Palmitic Acid SCHEMBL28997189 0.81 GPR84 (0.59) GPR84PPARGPPARDPPARAHDAC11
Decanoic Acid SCHEMBL28996527 0.81 GPR84 (0.59) GPR84PPARGPPARDPPARAHDAC11
Stearic Acid SCHEMBL27587498 0.81 GPR84 (0.59) GPR84PPARGPPARDPPARAHDAC11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105764980-A Surface treatment agent 大金工业株式会社 2016-07-13 CN disclosed
CN-105745272-A Aqueous emulsion surface treatment agent 大金工业株式会社 2016-07-06 CN disclosed