Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.96 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.67 |
| ▸ | TSHR | P16473 | 3/20 | 0.67 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.67 |
| ▸ | ESR1 | P03372 | 2/20 | 0.67 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.67 |
| ▸ | KDR | P35968 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | STS | P08842 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7181498 | 0.98 | LMNA (1.00) | LMNATDP1ALDH1A1TSHRSLC6A2 | |
| SCHEMBL130761 | 0.98 | LMNA (1.00) | LMNATDP1ALDH1A1TSHRSLC6A2 | |
| Water SCHEMBL28012190 | 0.96 | LMNA (0.96) | LMNATDP1ALDH1A1TSHRSLC6A2 | |
| SCHEMBL30886680 | 0.96 | LMNA (0.96) | LMNATDP1ALDH1A1TSHRSLC6A2 | |
| Hydrochloric Acid SCHEMBL27605432 | 0.96 | LMNA (0.96) | LMNATDP1ALDH1A1TSHRSLC6A2 | |
| SCHEMBL4465574 | 0.96 | LMNA (0.96) | LMNATDP1ALDH1A1TSHRSLC6A2 | |
| SCHEMBL28387455 | 0.96 | LMNA (0.96) | LMNATDP1ALDH1A1TSHRSLC6A2 | |
| Methane SCHEMBL28760616 | 0.96 | LMNA (0.96) | LMNATDP1ALDH1A1TSHRSLC6A2 | |
| Alcohol SCHEMBL27464334 | 0.94 | LMNA (0.92) | LMNATDP1ALDH1A1TSHRSLC6A2 | |
| Benzoic Acid SCHEMBL29000838 | 0.92 | LMNA (0.89) | LMNATDP1ALDH1A1TSHRSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105726494-B | Andrographolide nano suspension composition and its preparation method and application | 沈阳药科大学 | 2018-10-26 | — | — | CN | disclosed |
| CN-105726494-A | Nanometer andrographolide suspension composition, and preparation method and application of composition | 沈阳药科大学 | 2016-07-06 | — | — | CN | disclosed |