Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 7/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.34 |
| ▸ | AKT2 | P31751 | 3/20 | 0.34 |
| ▸ | AKT3 | Q9Y243 | 3/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL2806915 | 0.90 | MEN1 (0.35) | CNR2RAB9ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL2808732 | 0.88 | CNR2 (0.37) | CNR2RPS6KB1RAB9ACYP1A2CYP2D6 | |
| SCHEMBL2806917 | 0.84 | BDKRB1 (0.47) | — | |
| Trifluoroacetic Acid SCHEMBL2809036 | 0.81 | RAB9A (0.38) | CNR2RAB9ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL13128568 | 0.79 | BDKRB1 (0.45) | CNR2 | |
| SCHEMBL2808484 | 0.78 | B3GNT2 (0.33) | CNR2AKT1KCNH2CACNA1GCACNA1H | |
| SCHEMBL2805697 | 0.77 | RAB9A (0.41) | CNR2RAB9ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL27870326 | 0.77 | RAB9A (0.43) | CNR2RAB9ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL13160642 | 0.77 | MAPK10 (0.40) | CNR2 | |
| SCHEMBL2808635 | 0.76 | BDKRB1 (0.43) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130131075-A1 | NEW COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-05-23 | — | — | US | disclosed |
| US-20100240669-A1 | NEW COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130131075-A1 | NEW COMPOUNDS | ADORA1, H1-10, P2RY11 | CNR2 882/4885RPS6KB1 719/4885RAB9A 347/4885 |
| US-20100240669-A1 | NEW COMPOUNDS | ADORA1, H1-10, P2RY11 | CNR2 882/4885RPS6KB1 719/4885RAB9A 347/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.