Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.34 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.34 |
| ▸ | ACACB | O00763 | 2/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28829369 | 0.89 | LMNA (0.35) | LMNASCN9ASCN10AACACBDDB1 | |
| SCHEMBL27940167 | 0.86 | MAPT (0.35) | LMNAACACB | |
| SCHEMBL15312561 | 0.83 | FEN1 (0.47) | SCN9AALOX5APFEN1BCHEHTR6 | |
| SCHEMBL15312469 | 0.83 | FEN1 (0.47) | SCN9AALOX5APFEN1BCHEHTR6 | |
| SCHEMBL9941771 | 0.80 | HTR2A (0.43) | SCN9ABTKFEN1 | |
| SCHEMBL27921522 | 0.79 | MEN1 (0.39) | LMNASCN9ASCN10ABTK | |
| SCHEMBL27921618 | 0.78 | DDB1 (0.37) | LMNASCN9ADDB1CRBNBTK | |
| SCHEMBL15312555 | 0.77 | KDM4E (0.47) | SCN9AALOX5APFEN1HTR6 | |
| SCHEMBL27939961 | 0.76 | DDB1 (0.36) | LMNASCN9ASCN10AACACBDDB1 | |
| SCHEMBL27939975 | 0.76 | DDB1 (0.36) | LMNASCN9ASCN10AACACBDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103347882-B | Substituted N- (1H-indazol-4-yl) imidazo [1,2-a ] pyridine-3-carboxamide compounds as type III receptor tyrosine kinase inhibitors | ARRAY BIOPHARMA INC. (US) | 2016-05-11 | — | — | CN | disclosed |