SCHEMBL28069213

SCHEMBL28069213

COC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)Cc1ccc(O)cc1

nearest known ligand 0.60

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ERAP2 Q6P179 8/20 0.60
IL1RN P18510 6/20 0.60
NPY4R P50391 2/20 0.59
NPY1R P25929 1/20 0.59
ERAP1 Q9NZ08 6/20 0.59
TSHR P16473 1/20 0.54
LNPEP Q9UIQ6 2/20 0.53
FOLH1 Q04609 1/20 0.52
BIRC2 Q13490 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28069215 1.00 ERAP2 (0.60) ERAP2IL1RNNPY4RNPY1RERAP1
SCHEMBL10902071 0.90 PPID (0.53) ERAP2IL1RNNPY4RNPY1RERAP1
SCHEMBL10900164 0.90 PPID (0.53) ERAP2IL1RNNPY4RNPY1RERAP1
SCHEMBL27431221 0.90 ERAP2 (0.62) ERAP2IL1RNNPY4RNPY1RERAP1
SCHEMBL27824405 0.89 ERAP2 (0.64) ERAP2IL1RNNPY4RNPY1RERAP1
SCHEMBL27824408 0.89 ERAP2 (0.64) ERAP2IL1RNNPY4RNPY1RERAP1
SCHEMBL23106759 0.88 BIRC2 (0.65) BIRC2
SCHEMBL10443850 0.88 BIRC2 (0.65) BIRC2
SCHEMBL29046832 0.88 BIRC2 (0.65) BIRC2
SCHEMBL10443852 0.88 BIRC2 (0.65) BIRC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104788537-B A kind of tetrapeptides compound and its preparation method and application 中国科学院长春应用化学研究所 2018-03-13 CN claimed
CN-105622718-A Cyclic dipeptide used for wound healing GOOD DOCTOR PHARMACEUTICAL GROUP CO LTD 2016-06-01 CN claimed
CN-105622718-A Cyclic dipeptide used for wound healing GOOD DOCTOR PHARMACEUTICAL GROUP CO LTD 2016-06-01 CN disclosed