Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 7/20 | 0.80 |
| ▸ | HTR2C | P28335 | 4/20 | 0.80 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.65 |
| ▸ | HTR1A | P08908 | 4/20 | 0.64 |
| ▸ | HTR2B | P41595 | 3/20 | 0.64 |
| ▸ | HTR1D | P28221 | 2/20 | 0.64 |
| ▸ | HTR1B | P28222 | 2/20 | 0.64 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.64 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.64 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.64 |
| ▸ | HTR1E | P28566 | 1/20 | 0.64 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.64 |
| ▸ | HTR7 | P34969 | 1/20 | 0.64 |
| ▸ | HTR6 | P50406 | 1/20 | 0.64 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24178315 | 1.00 | HTR2A (0.80) | HTR2AHTR2CGPR84HTR1AHTR2B | |
| SCHEMBL274680 | 1.00 | HTR2A (0.80) | HTR2AHTR2CGPR84HTR1AHTR2B | |
| SCHEMBL29528195 | 1.00 | HTR2A (0.80) | HTR2AHTR2CGPR84HTR1AHTR2B | |
| SCHEMBL21292743 | 0.89 | HTR2A (1.00) | HTR2AHTR2CGPR84HTR1AHTR2B | |
| SCHEMBL19412024 | 0.89 | HTR2A (1.00) | HTR2AHTR2CGPR84HTR1AHTR2B | |
| SCHEMBL5555870 | 0.89 | HTR2A (1.00) | HTR2AHTR2CGPR84HTR1AHTR2B | |
| SCHEMBL3173954 | 0.89 | GPR84 (0.67) | HTR2AHTR2CGPR84HTR1AHTR2B | |
| Hydrochloric Acid SCHEMBL31143423 | 0.88 | HTR2A (0.97) | HTR2AHTR2CGPR84HTR1AHTR2B | |
| Hydrochloric Acid SCHEMBL20242634 | 0.88 | HTR2A (0.97) | HTR2AHTR2CGPR84HTR1AHTR2B | |
| SCHEMBL26996484 | 0.86 | HTR2A (0.79) | HTR2AHTR2CGPR84HTR1AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105636438-A | Pharmaceutical composition comprising an AMPK activator and a serotonin active agent and uses thereof | CHEN JIANHONG | 2016-06-01 | — | — | CN | claimed |