Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.64 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.53 |
| ▸ | HTR2C | P28335 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5577811 | 0.90 | DRD2 (0.58) | DRD2CHRM4SIGMAR1MEN1KMT2A | |
| SCHEMBL22928142 | 0.83 | DRD2 (0.62) | DRD2CHRM4SIGMAR1MEN1KMT2A | |
| SCHEMBL6353029 | 0.83 | DRD2 (0.62) | DRD2CHRM4SIGMAR1MEN1KMT2A | |
| SCHEMBL8479052 | 0.83 | DRD2 (0.78) | DRD2SIGMAR1HTR2C | |
| SCHEMBL8350724 | 0.81 | DRD2 (0.79) | DRD2CHRM4HTR2C | |
| SCHEMBL8775737 | 0.81 | MEN1 (0.74) | DRD2SIGMAR1MEN1KMT2AACHE | |
| SCHEMBL7480157 | 0.81 | DRD2 (0.74) | DRD2HTR2C | |
| SCHEMBL27732411 | 0.80 | KMT2A (0.56) | SIGMAR1MEN1KMT2AACHE | |
| SCHEMBL14067226 | 0.80 | DRD2 (0.72) | DRD2CHRM4HTR2C | |
| Hydrochloric Acid SCHEMBL7985714 | 0.79 | MEN1 (0.72) | DRD2SIGMAR1MEN1KMT2AACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105636438-A | Pharmaceutical composition comprising an AMPK activator and a serotonin active agent and uses thereof | CHEN JIANHONG | 2016-06-01 | — | — | CN | claimed |