SCHEMBL28069289

SCHEMBL28069289

C=C(C(N)=O)C(C)(C)C.C=CC(=O)NC(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
TSHR P16473 3/20 0.32
EGFR P00533 1/20 0.32
FGFR4 P22455 1/20 0.31
TDP1 Q9NUW8 2/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7608112 0.85 TDP1 (0.48) ALDH1A1CYP3A4CYP2C9CYP2C19MEN1
SCHEMBL8664301 0.83 ALDH1A1 (0.40) ALDH1A1CYP3A4CYP2C9CYP2C19MEN1
Acrylamide SCHEMBL998819 0.82 ALDH1A1 (0.50) ALDH1A1CYP3A4CYP2C9CYP2C19MEN1
SCHEMBL26705 0.82
SCHEMBL19457855 0.80 ALDH1A1 (0.44) ALDH1A1CYP3A4CYP2C9CYP2C19MEN1
Ammonia Solution, Strong SCHEMBL1036558 0.80 ALDH1A1 (0.44) ALDH1A1CYP3A4CYP2C9CYP2C19MEN1
SCHEMBL3468962 0.80 ALDH1A1 (0.44) ALDH1A1CYP3A4CYP2C9CYP2C19MEN1
Fluoride SCHEMBL21409814 0.80 ALDH1A1 (0.44) ALDH1A1CYP3A4CYP2C9CYP2C19MEN1
SCHEMBL30868898 0.80 ALDH1A1 (0.44) ALDH1A1CYP3A4CYP2C9CYP2C19MEN1
Hydrochloric Acid SCHEMBL29176180 0.80 ALDH1A1 (0.44) ALDH1A1CYP3A4CYP2C9CYP2C19MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103890579-B Tagged polymers, water treatment composition and the using method in aqueous system thereof BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) 2016-05-11 CN disclosed