Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 5/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.51 |
| ▸ | TACR1 | P25103 | 5/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL342516 | 0.92 | TACR1 (0.53) | SLC6A2SLC6A4SLC6A3KCNH2TACR1 | |
| SCHEMBL27732776 | 0.84 | CTSD (0.56) | SLC6A2SLC6A4SLC6A3KCNH2TACR1 | |
| SCHEMBL3129065 | 0.82 | SLC6A2 (0.53) | SLC6A2SLC6A4SLC6A3KCNH2TACR1 | |
| SCHEMBL339983 | 0.81 | TACR1 (0.61) | SLC6A2SLC6A4SLC6A3KCNH2TACR1 | |
| SCHEMBL340756 | 0.80 | SLC6A2 (0.53) | SLC6A2SLC6A4SLC6A3KCNH2TACR1 | |
| SCHEMBL342224 | 0.79 | HTR2A (0.55) | SLC6A2SLC6A4SLC6A3KCNH2TACR1 | |
| SCHEMBL27712266 | 0.79 | TACR1 (0.58) | SLC6A2SLC6A4SLC6A3KCNH2TACR1 | |
| SCHEMBL27712416 | 0.79 | TACR1 (0.49) | SLC6A2SLC6A4SLC6A3KCNH2TACR1 | |
| SCHEMBL3127165 | 0.78 | SLC6A2 (0.55) | SLC6A2SLC6A4SLC6A3KCNH2TACR1 | |
| SCHEMBL27732420 | 0.78 | TACR1 (0.60) | SLC6A2SLC6A4SLC6A3KCNH2TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105636438-A | Pharmaceutical composition comprising an AMPK activator and a serotonin active agent and uses thereof | CHEN JIANHONG | 2016-06-01 | — | — | CN | disclosed |