Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | DHODH | Q02127 | 2/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | TPMT | P51580 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SELL | P14151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21257119 | 0.87 | DHODH (0.46) | TSHRALOX15HIF1ADHODHTP53 | |
| SCHEMBL21257134 | 0.86 | ALOX15 (0.46) | TSHRALOX15HIF1ACA12CA1 | |
| SCHEMBL21257103 | 0.86 | ALOX15 (0.46) | TSHRALOX15HIF1ACA12CA1 | |
| SCHEMBL17114298 | 0.84 | TSHR (0.48) | TSHRALOX15HIF1ACA12CA1 | |
| SCHEMBL145349 | 0.83 | DHODH (0.58) | TSHRALOX15HIF1ACA12CA1 | |
| SCHEMBL21257102 | 0.82 | TSHR (0.46) | TSHRALOX15HIF1ACA12CA1 | |
| SCHEMBL17114228 | 0.82 | TSHR (0.46) | TSHRALOX15HIF1ACA12CA1 | |
| SCHEMBL16271136 | 0.80 | DHODH (0.56) | TSHRALOX15HIF1ACA12CA1 | |
| SCHEMBL12203147 | 0.80 | DHODH (0.57) | TSHRALOX15HIF1ACA12CA1 | |
| SCHEMBL15521765 | 0.80 | DHODH (0.57) | TSHRALOX15HIF1ACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105732678-B | Rare earth organic framework materials for biological tissue and the sensing imaging of cell interior fluorescence temperature and preparation method thereof | 浙江大学 | 2017-10-13 | — | — | CN | claimed |
| CN-105732678-B | Rare earth organic framework materials for biological tissue and the sensing imaging of cell interior fluorescence temperature and preparation method thereof | 浙江大学 | 2017-10-13 | — | — | CN | disclosed |
| CN-105732678-A | Rare-earth organic framework material for fluorescent temperature sensation imaging in biological tissue and cells and preparation method thereof | 浙江大学 | 2016-07-06 | — | — | CN | disclosed |