Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.76 |
| ▸ | RAB9A | P51151 | 1/20 | 0.70 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20818012 | 0.87 | TDP1 (1.00) | TDP1RAB9APOLBKDM4EALDH1A1 | |
| SCHEMBL7373227 | 0.86 | TDP1 (0.76) | TDP1RAB9AALDH1A1MAPTGAA | |
| SCHEMBL620646 | 0.86 | TDP1 (0.76) | TDP1RAB9AALDH1A1MAPTMAPK8 | |
| SCHEMBL10976046 | 0.85 | TDP1 (0.67) | TDP1RAB9APOLBALDH1A1MAPK8 | |
| SCHEMBL2779334 | 0.84 | RAB9A (0.76) | TDP1RAB9APOLBL3MBTL1KDM4E | |
| SCHEMBL2924686 | 0.84 | RAB9A (0.76) | TDP1RAB9APOLBL3MBTL1KDM4E | |
| SCHEMBL5749934 | 0.83 | TDP1 (0.72) | TDP1RAB9AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL28734386 | 0.83 | TDP1 (0.72) | TDP1RAB9AKDM4EALDH1A1DRD1 | |
| SCHEMBL28662140 | 0.82 | RAB9A (1.00) | TDP1RAB9APOLBL3MBTL1KDM4E | |
| SCHEMBL27653419 | 0.82 | TDP1 (0.67) | TDP1RAB9AKDM4EALDH1A1DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106543167-B | Isothiazole compound and application thereof | 沈阳中化农药化工研发有限公司 | 2021-12-03 | — | — | CN | disclosed |
| CN-105732585-B | Replace fragrant oxy picolinate class compound and application thereof | 沈阳中化农药化工研发有限公司 | 2019-03-01 | — | — | CN | disclosed |
| CN-105732585-A | Substituted aryloxypyridine compound and application thereof | 沈阳中化农药化工研发有限公司 | 2016-07-06 | — | — | CN | disclosed |