Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 5/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.48 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acridine SCHEMBL29277654 | 0.98 | SLC2A1 (0.51) | SLC2A1HRH3CACNA2D1ALDH1A1L3MBTL1 | |
| Quinoline SCHEMBL27785832 | 0.82 | ALDH1A1 (0.49) | SLC2A1HRH3ALDH1A1L3MBTL1 | |
| Acridine SCHEMBL28232031 | 0.80 | ALDH1A1 (0.65) | ALDH1A1TLR8GLAMAPTHPGD | |
| Acridine SCHEMBL27681561 | 0.80 | ALDH1A1 (0.65) | ALDH1A1TLR8GLAMAPTHPGD | |
| Acridine SCHEMBL28205217 | 0.78 | ALDH1A1 (0.62) | ALDH1A1TLR8GLAMAPTHPGD | |
| Acridine SCHEMBL29014290 | 0.78 | ALDH1A1 (0.68) | ALDH1A1TLR8GLAMAPTHPGD | |
| SCHEMBL10809994 | 0.76 | HRH3 (0.64) | HRH3 | |
| Propane SCHEMBL27953378 | 0.76 | HRH3 (0.62) | HRH3MAPT | |
| SCHEMBL7170819 | 0.76 | HRH3 (0.52) | HRH3ALDH1A1L3MBTL1 | |
| SCHEMBL7155350 | 0.74 | HRH3 (0.55) | HRH3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105636438-A | Pharmaceutical composition comprising an AMPK activator and a serotonin active agent and uses thereof | CHEN JIANHONG | 2016-06-01 | — | — | CN | disclosed |